Sexual dimorphism in innate immunity

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Sexual dimorphism in innate immunity.

OBJECTIVE To establish whether variation in innate immunity, as measured by the level of tumor necrosis factor (TNF) in lipopolysaccharide (LPS)-stimulated whole-blood culture, is related to sex or HLA. METHODS Normal volunteers (72 women, 159 men) completed questionnaires and donated peripheral blood specimens. Blood samples were exposed to LPS in a 4-hour in vitro culture, and supernatants ...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 2002

ISSN: 0004-3591,1529-0131

DOI: 10.1002/1529-0131(200201)46:1<250::aid-art10064>3.0.co;2-t